Increasing the yield of nitrodiphenylamines in base/palladium-catalysed nitrohalobenzene/aromatic amine reactions by using a base which has been milled and optionally also dried

摘要

Solid alkali(ne earth) carbonates, alcoholates and/or hydroxides used as bases with Pd catalysts in the preparation of nitrodiphenylamines are milled, and optionally also dried, prior to use. Preparation of nitrodiphenylamines by reaction of nitrohalobenzenes with aromatic amines in presence of solid alkali(ne earth) metal carbonates, alcoholates and/or hydroxides as bases and Pd phosphine complexes or combinations of other Pd complexes (or compounds) with phosphines as catalysts is such that the bases are milled, and optionally also dried, prior to use.