PROCESS FOR PRODUCING ISOCOUMARINS AND INTERMEDIATES FOR THE SAME
摘要
<p>Provided is a process for producing an isocoumarin-3-yl-acetic acid derivative, characterized by reacting a homophthalic acid derivative represented by formula (a): (wherein Rc, R2 and R are mainly protecting groups) with a malonic acid derivating represented by formula (IV): (wherein R is an organic group including a lower alkyl group; R3 is a protecting group for a carboxyl group; and X is a halogen atom or a -OM group (wherein M is alkaline metal or alkaline earth metal)). According to the above process, various isocoumarin-3-yl-acetic acid derivatives can efficiently be provided.</p>
申请公布号
WO0107429(A1)
申请公布日期
2001.02.01
申请号
WO2000JP04371
申请日期
2000.06.30
申请人
MERCIAN CORPORATION;ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI