| 摘要 |
A process for preparing a pharmaceutically-active extract of the root of a plant of the family Valerianacae, specifically, <i>Valeriana officinalis</i> L., is described. This process comprises the steps of adding the roots to an alcoholic extraction solvent to form a mixture, wherein the alcoholic extraction solvent comprises between approximately 50 % to approximately 100 % (v/v) in a remainder of water, and heating the mixture to a temperature of between approximately 70 DEG C to approximately 80 DEG C for a period of at least approximately two hours. By this process valerenic acid is obtained in the extract, and the extract has a content of valepotriates and valepotriate degradation products or derivatives that is substantially reduced with respect to the content of valepotriates in the roots, and has a content of valerenic acids that is not substantially reduced with respect to the content of valerenic acids in the roots. Also preferably, the content of volatile oils in the extract is also not substantially with respect to the content of volatile oils in the roots. A pharmaceutically-active extract of the root of a plant of the family Valerianaceae is also described. This extract is obtained by a process comprising the steps of adding the roots to an alcoholic extraction solvent to form a mixture, wherein the alcoholic extraction solvent comprises between approximately 50 % (v/v) to approximately 100 % (v/v) in a remainder of water, and heating the mixture to a temperature of between approximately 70 DEG C to approximately 80 DEG C for a period of at least approximately two hours. This extract may be used in the formulation of an ingestible form, preferably exhibiting sedative and/or muscle relaxant, and/or anxiolytic activity.
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