发明名称 |
ANTISENSE MODULATION OF JUN N-TERMINAL KINASE KINASE-1 EXPRESSION |
摘要 |
<p>Antisense compounds, compositions and methods are provided for modulating the expression of Jun N-terminal Kinase Kinase-1. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Jun N-terminal Kinase Kinase-1. Methods of using these compounds for modulation of Jun N-terminal Kinase Kinase-1 expression and for treatment of diseases associated with expression of Jun N-terminal Kinase Kinase-1 are provided.</p> |
申请公布号 |
WO0107456(A1) |
申请公布日期 |
2001.02.01 |
申请号 |
WO1999US29589 |
申请日期 |
1999.12.14 |
申请人 |
ISIS PHARMACEUTICALS, INC.;WARD, DONNA, T.;COWSERT, LEX, M. |
发明人 |
WARD, DONNA, T.;COWSERT, LEX, M. |
分类号 |
C12N15/09;A61K31/7088;A61K31/7115;A61K31/712;A61K31/7125;A61K38/00;A61K48/00;A61P43/00;C07H21/00;C12N15/113;(IPC1-7):C07H21/04;C12Q1/68;C12N15/00 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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