CARBONYLATION REACTIONS

摘要

A continuous process for carrying out carbonylation reactions has an alkene, alkyne or alcohol substrate reacted with carbon monoxide using a heterogeneous catalyst and with or without use of a solvent medium. At least one component is under supercritical or near critical conditions. One or more of the reaction conditions of temperature, pressure, residence time, flow rate and catalyst can be controlled so as to achieve optional yield and/or selectivity.