NEW VITAMIN D DERIVATIVES WITH CYCLIC SUBSTRUCTURES IN THE SIDE CHAINS, METHOD AND INTERMEDIATES FOR THEIR PRODUCTION AND THEIR USE IN THE PREPARATION OF MEDICAMENTS

摘要

The invention relates to vitamin D derivatives of the formula (I), wherein Z is an optionally substituted carbocyclic or heterocyclic, optionally aromatic or heteroaromatic 5- or 6-membered ring or an optionally substituted condensed ring structure that consists of a 5-membered and a 6-membered ring or of two 6-membered rings, and Q, R1-R4, X1-X2 and Y1-Y3 have the meanings given in the description. The invention further relates to a method for their production, to the use of said derivatives in the preparation of medicaments, and to a method for producing compounds of the formula (Iia), wherein E represents any side chain, and R7, R8, Y2, Y3 and Y5 have the meanings given in the description. The invention also relates to the intermediates of both methods.