发明名称 Friedel-Crafts-Acylierung im statischen Mikromischer
摘要 The invention relates to a method for the Friedel-Crafts acylation of organic compounds. The method is characterised in that a) a solution is produced which contains an acylation reagent and a strong acid; b) this solution is mixed in an intensive manner with an organic compound, preferably an aromatic or heteroaromatic compound in liquid or solution form c) in a temperable microreactor, whose outlet channel is optionally connected to a temperable capillary which measures several metres, during a sufficient dwell time. The product formed during the reaction is isolated from the collected reaction mixture.
申请公布号 DE19935691(A1) 申请公布日期 2001.02.01
申请号 DE19991035691 申请日期 1999.07.29
申请人 MERCK PATENT GMBH 发明人 WURZIGER, HANNS;FABIAN, KAI;SCHWESINGER, NORBERT
分类号 C07D307/80;B01J14/00;B01J19/00;C07B41/06;C07B61/00;C07C45/46;C07C49/84;(IPC1-7):C07C45/46 主分类号 C07D307/80
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