| 摘要 |
A vascular permeability suppressant includes an oxaspirooctane derivative of the general formula (I):[wherein, R1 represents, for example, lower alkylcarbamoyl group or protected carbamoyl group, R2 represents lower alkoxyl group, and R3 represents the formula:or a pharmaceutically acceptable salt thereof, together with a pharmaceutically acceptable carrier. Particularly, for example, an agent that can prevent retention of carcinomatous pleural effusion or carcinomatous ascites.
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