发明名称 Stabilized carbapenem intermediates and improved process for carbapenem synthesis
摘要 A stabilized carbapenem intermediate compound represented by the formula 1:or a salt thereof is disclosed, wherein P represents a carboxyl protecting group and X represents a charge balancing group.In addition, a process for synthesizing a compound represented by formula 2:is disclosed wherein X+ is a charge balancing group, comprising: deprotecting a compound of the formula 1 to produce a compound 2.
申请公布号 US6180783(B1) 申请公布日期 2001.01.30
申请号 US19980093813 申请日期 1998.06.09
申请人 MERCK & CO., INC. 发明人 WILLIAMS JOHN M.;SKERLJ RENATO T.;BRANDS KAREL M. J.;DOLLING ULF H.;JOBSON RONALD B.
分类号 C07D477/20;(IPC1-7):C07D477/20 主分类号 C07D477/20
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