发明名称 Composite gel microparticles as active principle carriers
摘要 The invention relates to vectors for delivering medicinal, nutritional, plant-protection or cosmetic active principles, these delivery particles being of small, controllable and adjustable particle size, which protect the active principle, and being biocompatible, biodegradable, non-immunogenic, stable and free of solvent. The particles do not denature the active principle and allow the active principle to be released. The microparticles of the invention are of a cohesive structure made of a physicochemically stable and integral composite gel which includes an oil such as coconut oil, an aqueous phase and a linear, non-crosslinked copolyamino acid of Leu/Glu type (random or diblock). The microparticles have a controllable and adjustable size of between 0.05 and 500 mum.
申请公布号 US6180141(B1) 申请公布日期 2001.01.30
申请号 US19990147032 申请日期 1999.01.04
申请人 FLAMEL TECHNOLOGIES 发明人 LEMERCIER ALAIN;MEYRUEIX REMI;HUILLE SYLVAIN;SOULA GERARD
分类号 A23L1/00;A61K8/02;A61K8/31;A61K8/37;A61K8/44;A61K8/64;A61K8/73;A61K8/89;A61K8/891;A61K8/92;A61K8/97;A61K9/16;A61K9/50;A61K9/51;A61K31/70;A61K38/00;A61K38/21;A61K38/28;A61K38/43;C07H3/00;C07H21/02;C07H21/04;C08B37/10;C08L83/04;(IPC1-7):A61K9/14 主分类号 A23L1/00
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