发明名称 Stable aqueous suspension of micronized tixocortol pivalate useful in collutory also containing surfactant and a viscosity regulator, for treating local inflammation e.g. laryngitis
摘要 An aqueous suspension (A) of tixocortol pivalate (I) comprises: (a) suspended (I) particles of average diameter 0.5-20 (preferably 1-10) mu m; (b) a surfactant; (c) a viscosity regulator; and (d) water, plus conventional additives. Independent claims are included for: (i) a collutory (i.e. aerosol of droplets) based on (A), having a volume of 100-300 (preferably 150-220) micro l; (ii) a packaged product comprising a container containing (A) and fitted with a dosing pump; and (iii) the preparation of (A), by preparing an aqueous solution comprising (b)-(d) and optionally a further active agent, then suspending (I) in the solution.
申请公布号 FR2796553(A1) 申请公布日期 2001.01.26
申请号 FR19990009556 申请日期 1999.07.22
申请人 WARNER LAMBERT COMPANY 发明人 DOAT BERNARD
分类号 A61K9/10;A61K;A61K31/54;A61K31/57;A61K31/573;A61K47/00;A61K47/10;A61K47/14;A61K47/18;A61P11/00;A61P11/04;A61P27/16;A61P29/00;A61P31/00;(IPC1-7):A61K31/57 主分类号 A61K9/10
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