发明名称 Multifunctional enzyme having N-terminal sequence IVGGXEVTPHAYPWQVGLFIDDMYF, where X is any amino acid
摘要 A multifunctional enzyme derived from crustaceans or fish. The enzyme has at least one of chymotrypsin, trypsin, elastase, collagenase and exo-peptidase activity, and a molecular weight between about 20 kD and about 40 kD as determined by SDS PAGE. Preferably, the multifunctional enzyme has substantial anti cell-cell adhesion activity. Preferably, the multifunctional enzyme has substantial homology with the krill multifunctional enzyme. These enzymes are useful for treating viral infections such as herpes outbreaks, fungal, bacterial or parasitic infections, including the primary and secondary infections of leprosy, colitis, ulcers, hemorrhoids, corneal scarring, dental plaque, acne, cystic fibrosis, blood clots, wounds, immune disorders including autoimmune disease and cancer. Additionally, disclosed is a method of purifying the multifunctional enzyme, and to a preparation of essentially purified multifunctional enzyme.
申请公布号 NZ302984(A) 申请公布日期 2001.01.26
申请号 NZ19960302984 申请日期 1996.02.08
申请人 PHAIRSON MEDICAL INCORPORATED 发明人 DE FAIRE, JOHAN;FRANKLIN, RICHARD L;KAY, JOHN
分类号 C12N9/14;A61K8/96;A61K8/98;A61K35/56;A61K38/00;A61K38/43;A61K38/48;A61K38/55;A61P11/00;A61P17/00;A61P17/02;A61P27/02;A61P27/14;A61P29/00;A61P31/00;A61P31/04;A61P31/12;A61P35/00;A61P37/00;A61P37/08;A61P43/00;A61Q11/00;C12N9/00;C12N9/48;C12N9/64;C12N9/66;(IPC1-7):C12N9/50;C12N9/76 主分类号 C12N9/14
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