Targeted ultrasound contrast agents are described. The contrast agents are porous particles of an inorganic material containing an entrapped gas or liquid and having an average particle diameter of about 0.05 to 500 microns. The outer surfaces of the particles incorporate a targeting ligand to target delivery of the contrast agent.
申请公布号
WO0105438(A1)
申请公布日期
2001.01.25
申请号
WO1999US16804
申请日期
1999.07.22
申请人
DU PONT PHARMACEUTICALS COMPANY
发明人
GLAJCH, JOSEPH, L.;CARPENTER, ALAN, P., JR.;CHEESMAN, EDWARD, H.
