EXPRESSION OF DNA OR PROTEINS IN <i>C. ELEGANS</i>
摘要
DNA fragments from the promoter region of the <i>C. elegans</i> UL6 gene which are capable of functioning as promoters directing gene expression in the excretory cell of <i>C. elegans</i> are provided and also expression vectors and transgenic <i>C. elegans</i> containing these fragments. Also provided are screening methods performed in <i>C. elegans</i> for identifying compounds or mutations which have an effect on the morphology of the excretory canal. Compounds identified using these screening methods may have therapeutic potential in the treatment of a range of diseases for which the <i>C. elegans</i> excretory canal serves as a model.
