发明名称 ENTEROCYTE GROWTH FACTORS AND METHOD FOR THEIR ISOLATION
摘要 The invention refers to 20 enterocyte growth factors - EGFs with enhanced effectiveness as to their influence on the speed of morphogenesis, 9 of them stimulate cell growth and 11 ones inhibit cell growth. The method is in isolating them from intestinal mucosa from warm-blooded animals. Mucosa can also be from large intestines from warm-blooded animals. It is possible that mucosa is both from small and large intestines from warm-blooded animals with chemical carcinogenesis, and the ratio between the inhibiting and stimulating enterocyte growth factors in biomass can vary within 6:4 to 5:5, or 5:5.001 to 4:6, or 8:2 to 7:3. The method is characterised by its higher productivity and higher resolution with regard to fractions, and allows for wider possibilities for the production of more qualitatively different EGFs.
申请公布号 WO0047605(A3) 申请公布日期 2001.01.25
申请号 WO2000BG00005 申请日期 2000.02.07
申请人 TCHOBANOVA, ALEXANDRA ANGELOVA;ALEXANDROV, CHRISTO ALEXANDROV;TRIFONOV, BORISLAV BORISOV;ROUSSEV, GEORGE KONSTANTINOV 发明人 ALEXANDROV, CHRISTO ALEXANDROV;TRIFONOV, BORISLAV BORISOV;ROUSSEV, GEORGE KONSTANTINOV
分类号 A61K38/00;C07K5/097;C07K9/00;C07K14/475;(IPC1-7):C07K14/47;C07K5/08 主分类号 A61K38/00
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