发明名称 |
ENTEROCYTE GROWTH FACTORS AND METHOD FOR THEIR ISOLATION |
摘要 |
The invention refers to 20 enterocyte growth factors - EGFs with enhanced effectiveness as to their influence on the speed of morphogenesis, 9 of them stimulate cell growth and 11 ones inhibit cell growth. The method is in isolating them from intestinal mucosa from warm-blooded animals. Mucosa can also be from large intestines from warm-blooded animals. It is possible that mucosa is both from small and large intestines from warm-blooded animals with chemical carcinogenesis, and the ratio between the inhibiting and stimulating enterocyte growth factors in biomass can vary within 6:4 to 5:5, or 5:5.001 to 4:6, or 8:2 to 7:3. The method is characterised by its higher productivity and higher resolution with regard to fractions, and allows for wider possibilities for the production of more qualitatively different EGFs.
|
申请公布号 |
WO0047605(A3) |
申请公布日期 |
2001.01.25 |
申请号 |
WO2000BG00005 |
申请日期 |
2000.02.07 |
申请人 |
TCHOBANOVA, ALEXANDRA ANGELOVA;ALEXANDROV, CHRISTO ALEXANDROV;TRIFONOV, BORISLAV BORISOV;ROUSSEV, GEORGE KONSTANTINOV |
发明人 |
ALEXANDROV, CHRISTO ALEXANDROV;TRIFONOV, BORISLAV BORISOV;ROUSSEV, GEORGE KONSTANTINOV |
分类号 |
A61K38/00;C07K5/097;C07K9/00;C07K14/475;(IPC1-7):C07K14/47;C07K5/08 |
主分类号 |
A61K38/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|