摘要 |
A controlled release pellet for releasing a poorly soluble active agent comprises a core containing the active agent (e.g. nifedipine, glibenclamide, griseofulvin, oxaprozin, ibuprofen, diclofenac, nabumetone etc.), a polyethylene glycol and a carrier; the core having a coating comprising a water soluble cellulose and a water insoluble acrylic polymer. A disintegrating agent is preferably included in the core.
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申请人 |
CENES DRUG DELIVERY LIMITED;ADESUYI, CHARLES, TOKUNBO;LIVINGSTONE, MARK, ALEXANDER;MONTIETH, DAVID;DAWSON, GORDON, FINDLAY |
发明人 |
ADESUYI, CHARLES, TOKUNBO;LIVINGSTONE, MARK, ALEXANDER;MONTIETH, DAVID;DAWSON, GORDON, FINDLAY |