| 摘要 |
<p>Compounds of general formula (I), prodrugs of the same, pharmaceutically acceptable salts of both, or solvates of them, exhibiting sPLA2-inhibitory activities. In said formula R1 is C1-C20 alkyl, C2-C20 alkenyl, C2-C20 alkynyl, a carbocyclic group, a heterocyclic group, or the like; R2 is COCONH¿2? or the like; Q?1¿ is nitrogen or C-R4; either of R?3 and R4 is (L2¿)-(acid group) (wherein -L2 is a group connecting with an acid group and the length of the connecting group is 1 to 5), and the other is hydrogen; R?21 and R22¿ are each hydrogen or the like; X is -CR23R24- or the like (wherein R?23 and R24¿ are each hydrogen or the like); Y is -CR25R26- (wherein R?25 and R26¿ are each hydrogen or the like) or the like; Z is CH¿2? or the like; and the broken line represents the presence or absence of a bond.</p> |
