发明名称 |
METHODS FOR HIGHLY SELECTIVELY O-ALKYLATING AMIDE COMPOUNDS WITH THE USE OF COPPER SALTS |
摘要 |
<p>Compounds having one or more structures represented by general formula (I) as partial structure thereof, which are typified by pyrimidone and pyridone compounds, have two or more reaction sites in alkylation reactions. Accordingly, there is no process for producing O-alkylated products of these compounds at a high selectivity or such processes, if any, are applicable exclusively to those having limited structures. A process for selectivity O-alkylating such a compound as described above by converting it into the copper salt by using a monovalent copper compound such as copper suboxide and then reacting it with an alkylating agent having a leaving group in the presence of a phosphorus compound such as a phosphite. Pyrimidyloxy derivatives or pyridyloxy derivatives obtained by this reaction is useful as intermediates of pesticides or drugs. <CHEM></p> |
申请公布号 |
EP1070692(A1) |
申请公布日期 |
2001.01.24 |
申请号 |
EP19990937922 |
申请日期 |
1999.03.04 |
申请人 |
NIPPON SODA CO., LTD. |
发明人 |
TAKASE, MITSURU;MIYAZAWA, YASUYUKI;TSUBOKURA, SHIRO |
分类号 |
C07D239/52;(IPC1-7):C07B41/04;B01J27/228;B01J23/72 |
主分类号 |
C07D239/52 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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