摘要 |
Novel carbapenem derivatives, represented by the following formula (I), having a substituted or unsubstituted imidazo¢5,1-b!thiazolium-6-ylmethyl group at the 2-position are disclosed. The compounds represented by the formula (I) have potent antibacterial activity against a wide spectrum of bacteria from Gram-positive bacteria to Gram-negative bacteria including Pseudomonas aeruginosa and, in addition, have potent antibacterial activity against various .beta.-lactamase-producing bacteria and MRSA and are very stable against DHP-1. (see formula I)
|
申请人 |
MEIJI SEIKA KABUSHIKI KAISHA |
发明人 |
AIHARA, KAZUHIRO;TOYOOKA, YUMIKO;KANO, YUKO;ISHII, MIYUKI;SHIOKAWA, SOHJIRO;ATSUMI, KUNIO;SASAKI, TOSHIRO;IWAMATSU, KATSUYOSHI;SETSU, FUMIHITO;TAMURA, ATSUSHI |