发明名称 |
METHOD OF PREPARING ENANTIOMERICALLY PURE IMIDAZOLYL COMPOUNDS, ENANTIOMERICALLY PURE ACID ADDITION SALT OF IMIDAZOLYL AND D-OR L-PYROGLUTAMIC ACID, AND HYDROCHLORIDE MONOHYDRATE OF ENANTIOMERICALLY PURE IMIDAZOLYL COMPOUNDS |
摘要 |
biochemistry. SUBSTANCE: described is method of preparing enantiomerically pure imidazolyl of general formula I: , enantiomerically pure addition salt of imidazolyl and hydrochloride monohydrate of enantiomerically pure imidazolyl compound of general formula I wherein R1 is as defined above. The resulting compounds have biological activity with respect to 5HT antagonists. EFFECT: more efficient preparation method. 18 cl, 5 ex |
申请公布号 |
RU2162085(C2) |
申请公布日期 |
2001.01.20 |
申请号 |
RU19960120366 |
申请日期 |
1996.10.09 |
申请人 |
DJUFAR INTERNEHSHNL RISERCH B.V. |
发明人 |
PAULJUS FRANSISKUS KORNELIS VAN DER MEJ;JAN-MARTEN VERBEK |
分类号 |
C07D487/06;A61K31/41;A61K31/415;A61K31/435;A61K31/473;A61P43/00;C07D233/54;C07D403/06;C07D471/06;(IPC1-7):C07D403/06 |
主分类号 |
C07D487/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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