发明名称 MODELE D'ETUDE DE LA PROGRESSION DE METASTASES PULMONAIRES SPONTANEES, ET SON UTILISATION DANS LE CRIBLAGE DE MEDICAMENTS
摘要 The invention concerns the use of a human pulmonary carcinoma cell line, in particular derived from the NCI-H460 cell line, having the following properties: it expresses independently a fluorescent protein, it is stable towards said protein, it is capable of producing, after being injected into an animal, without orthotopic graft, spontaneous fluorescent pulmonary metastases, it expresses the fluorescent protein in sufficient amount such that a single micrometastasis in said animal can be detected, for early screening of medicine acting on pulmonary metastases.
申请公布号 FR2796393(A1) 申请公布日期 2001.01.19
申请号 FR19990009164 申请日期 1999.07.15
申请人 INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE INSERM 发明人 DIARRA MEHRPOUR MARYAM;PARIS SEBASTIEN
分类号 C07K14/435;C12N5/08;(IPC1-7):C12N5/10;C12N15/65 主分类号 C07K14/435
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