发明名称 METHOD FOR CONTROLLED PRODUCTION OF ULTRAFINE MICROPARTICLESAND NANOPARTICLES
摘要 The invention concerns ultrafine microparticles and nanoparticles, and a method for controlled production thereof in the absence of or with minimum water, in the absence of plasticizers or under reduced temperature constrain t. The method is characterised in that it consists in subjecting a matrix material to a high pressure homogenising process in an anhydrous or dry or l ow temperature medium, preferably at room temperature (20~C) and in particular below the freezing point of water. Said process brings about controlled fine grinding and reduces to a minimum the damaging influence of the chemical stability of the homogenised material.
申请公布号 CA2375992(A1) 申请公布日期 2001.01.18
申请号 CA20002375992 申请日期 2000.07.10
申请人 PHARMASOL GMBH 发明人 KRAUSE, KARSTEN;MULLER, RAINER HELMUT;MADER, KARSTEN
分类号 A61J3/02;A61K8/02;A61K8/25;A61K8/64;A61K8/65;A61K8/73;A61K9/14;A61K9/51;A61K31/175;A61K31/192;A61K31/196;A61K31/337;A61K31/485;A61K31/513;A61K31/55;A61K31/573;A61K38/00;A61K47/02;A61K47/30;A61K47/32;A61K47/34;A61K47/36;A61K47/42;B02C19/00;C08J3/12;(IPC1-7):A61K9/14 主分类号 A61J3/02
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