发明名称 |
CALCIUM-CONTAINING STRUCTURES AND METHODS OF MAKING AND USING THE SAME |
摘要 |
The present invention generally relates to calcium-containing structures and methods of using the structures. In one aspect, the porous or hollow microstructures or particulates contain nitric oxide or a nitric oxide formi ng compound. The hollow calcium containing microstructures are used in conjunction with bone tissues/by-products to augment bone defects and extend the supply of bone tissues/by-products for bone augmentation. Bonding agents, such as calcium cements, are also used in the preparation of the hollow calcium microstructures combined with bone tissues/by-products or for use in preparing the hollow microstructures. The calcium-containing microstructures of the present invention are also useful as delivery vehicles of nitric oxide and/or nitric oxide containing or producing compounds for a variety of in vitro and in vivo uses. Calcium containing contoured substrates upon which cells/tissues can be grown in vitro for replacement and repair of tissues in vivo that conform in size and shape to the tissue surface to be replaced are also provided.
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申请公布号 |
CA2669457(A1) |
申请公布日期 |
2001.01.18 |
申请号 |
CA20002669457 |
申请日期 |
2000.07.07 |
申请人 |
CAP BIOTECHNOLOGY INC. |
发明人 |
STARLING, BRIAN L.;STEPHAN, JAMES E. |
分类号 |
A61K47/02;A61K9/00;A61K9/50;A61K31/198;A61K33/00;A61K33/06;A61K35/12;A61K38/44;A61K45/06;A61K47/30;A61K47/34;A61L27/12;A61L27/36;A61L27/50;A61L27/54;C12N5/00;C12N5/077 |
主分类号 |
A61K47/02 |
代理机构 |
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主权项 |
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地址 |
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