CYANOVIRIN CONJUGATES, MATRIX-ANCHORED CYANOVIRIN AND ANTI-CYANOVIRIN ANTIBODY, AND RELATED COMPOSITIONS AND METHODS OF USE

摘要

The present invention provides, among other things, methods of removing virus from a sample, compositions treated in accordance with such methods, a composition comprising a naturally-occurring non- infectious HIV comprising gp120, a composition comprising a solid support matrix to which is attached a cyanovirin or a conjugate thereof, a conjugate comprising a cyanovirin coupled to an anti-cyanovirin antibody or at least one effector component, a composition comprising such a conjugate, methods of inhibiting prophylactically or therapeutically a viral infection of a host, methods of inducing an immune response to a virus in an animal, and a matrix-anchored anti-cyanovirin antibody.