IN VITRO RECONSTITUTION OF SEGMENTED NEGATIVE-STRAND RNA VIRUSES
摘要
There is disclosed a method for generating in cultured cells infectious viral particles of a segmented negative-strand virus by an entirely vector-based system without the aid of a helper virus. The method may, for example, be particularly useful for producing modified influenza viruses.
申请公布号
WO0104333(A1)
申请公布日期
2001.01.18
申请号
WO2000GB02710
申请日期
2000.07.14
申请人
ISIS INNOVATION LIMITED;MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY;BROWNLEE, GEORGE, GOW;FODOR, ERVIN;PALESE, PETER;GARCIA-SASTRE, ADOLFO
