摘要 |
<p>Disclosed is a compound of the general formula (I), wherein R1 is A, R1, R2 and R3 are each independently H, Ph or Het, or together a C4-5 alkylene group; Het is a mono- or dicyclic aromatic heterocycle having 1 to 4 nitrogen; Ph is a phenyl goup, optionally by one or two atoms of F, Cl or Br; A is an C1-6 alkyl group; and the physiologically unobjectionable salts thereof, which compound exhibits antiarrhythmic properties and is active as an inhibitor of the cellular Na+/H+ antiporter. Also disclosed is a method of preparing said compound of the formula (I) and pharmaceuticals it containing.</p> |