METHANESULFONATE OF (E)-3-[2-N-BUTYL-1{(4-CARBOPHENYL)METHYL}- -1H-IMIDAZOL-5-YL]-2-(2-THIENYL)METHYL-2-PROPENOIC ACID, PROCESS OF ITS PREPARATION, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, ITS USE

摘要

The present invention relates to new imidazolyl-alkenoic acids which are angiotensin II receptor antagonists and are useful in regulating hypertension induced or exacerbated by angiotensin II, and in the treatment of congestive heart failure, renal failure, and glaucoma. This invention also relates to pharmaceutical compositions containing these compounds and methods for using these compounds as antagonists of angiotensin II, as antihypertensive agents and as agents for treating congestive heart failure, renal failure, and glaucoma.