MONOCLONAL ANTIBODY ANTI ALPHA V-INTEGRIN, A FRAGMENT THEREOF, METHOD FOR PREPARING THE SAME, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME AND ITS USE

摘要

The invention relates to a novel monoclonal antibody and a hybridoma cell line producing said antibody. The monoclonal antibody, a preferred embodiment of which is named 14D9.F8, has the following properties: reacting only with the alpha v-chain of human alpha v-integrins, and inhibiting selectively the attachment to the integrin substrate fibronectin of the alpha v beta 6-integrin bearing cell.