DRUG TARGET ISOGENES: POLYMORPHISMS IN THE OSTEOCLASTOGENESIS INHIBITORY FACTOR GENE

摘要

Polynucleotides comprising one or more of 24 novel single nucleotide polymorphisms in the human Osteoclastogenesis Inhibitory Factor (TNFRSF11B) gene are described. Compositions and methods for detecting one or more of these polymorphisms are also disclosed. In addition, various genotypes and haplotypes for TNFRSF11B gene that exist in the population are described.