<p>Antisense compounds, compositions and methods are provided for modulating the expression of PDK-1. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding PDK-1. Methods of using these compounds for modulation of PDK-1 expression and for treatment of diseases associated with expression of PDK-1 are provided.</p>
申请公布号
WO0061786(A3)
申请公布日期
2001.01.18
申请号
WO2000US09055
申请日期
2000.04.06
申请人
ISIS PHARMACEUTICALS, INC.;MONIA, BRETT, P.;COWSERT, LEX, M.