| 摘要 |
<p>Process for the preparation of compounds of general formula (I), in which R is hydrogen or a group of formula -SO2R1 R1 is C¿1-6?-alkyl; R?2¿ is hydrogen or C¿1-6?-alkyl; R?3¿ is C¿1-6?-alkyl; R?4¿ is C¿1-6?-alkyl, characterized in that, in a first stage, a compound of formula (II), in which R?3 and R4¿ have the abovementioned meaning, is reacted in the presence of a Lewis acid with 4-fluoro-benzonitrile to give a compound of general formula (III), in which R?3 and R4¿ have the abovementioned meaning and in a second stage the compound of formula (III) obtained is reacted with the compound of formula (IV), in which R and R2 have the abovementioned meaning, to give the final product of formula (I).</p> |
