发明名称 |
PROCESS FOR PRODUCING DIBENZOTHIAZEPINE DERIVATIVES |
摘要 |
A process for producing dibenzothiazepine derivatives typified by dibenzo[b,f][1,4]thiazepin-11-one which are usable as the starting material for producing 11-[4-(2-(2-hydroxyethoxy)ethyl)]-1-piperazinyldibenzothiazepine derivatives useful as a psychotropic drug, which comprises reacting a nitrobenzene derivative with a thiosalicylic acid derivative, reducing the thus obtained 2-nitro-2'-carboxy-diphenylsulfide derivative, and then further dehydrating and condensing the thus obtained 2-amino-2'-carboxy-diphenylsulfide derivative.
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申请公布号 |
WO0104106(A1) |
申请公布日期 |
2001.01.18 |
申请号 |
WO1999JP03719 |
申请日期 |
1999.07.09 |
申请人 |
UBE INDUSTRIES, LTD.;HARADA, KATSUMASA;NISHINO, SHIGEYOSHI;YOSHII, KIYOTAKA |
发明人 |
HARADA, KATSUMASA;NISHINO, SHIGEYOSHI;YOSHII, KIYOTAKA |
分类号 |
C07D281/16;A61K31/55;A61K31/554;A61P25/18;C07C319/14;C07C323/62;(IPC1-7):C07D281/16 |
主分类号 |
C07D281/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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