发明名称 Process for preparing human erythropoietin
摘要 In the present invention there is disclosed a process for preparing human erythropoietin. The preparation process is characterized by cultivating in a suitable medium eukaryotic host cells containing a DNA sequence shown in Table 3 form a ATG sequence encoding initial Met up to AGA sequence encoding terminal Arg being attached to an expression check sequence, and so prepared erythropoietin is subsequently separated from both the cells and medium.
申请公布号 CZ287620(B6) 申请公布日期 2001.01.17
申请号 CZ19990004314 申请日期 1999.12.02
申请人 GENETICS INSTITUTE, INC. 发明人 FRITSCH EDWARD;HEWICK RODNEY M.;JACOBS KENNETH;KAUFMAN RANDAL J.
分类号 C12N15/09;A61K35/12;A61K38/22;A61P7/00;C07H21/04;C07K1/20;C07K14/00;C07K14/505;C07K14/52;C12N1/16;C12N1/19;C12N1/20;C12N1/21;C12N5/10;C12N5/16;C12N5/18;C12N15/00;C12N15/10;C12N15/16;C12N15/63;C12N15/85;C12P21/00;C12P21/02;C12R1/19;C12R1/645;C12R1/91 主分类号 C12N15/09
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