| 发明名称 |
Sulfonamides and derivatives thereof that modulate the activity of endothelin |
| 摘要 |
<p>A compound of the following formula: <CHEM> or a pharmaceutically acceptable salt thereof, where Ar<2> is particularly phenyl, biphenyl or naphthyl and R<1> and R<2> are as defined herein, useful in the modulation of the activity of endothelin.</p> |
| 申请公布号 |
EP1069114(A2) |
申请公布日期 |
2001.01.17 |
| 申请号 |
EP20000119107 |
申请日期 |
1994.05.20 |
| 申请人 |
TEXAS BIOTECHNOLOGY CORPORATION |
发明人 |
CHAN, MING FAI;RAJU, BORE GOWDA;KOIS, ADAM;VERNER, ERIK JOEL;WU, CHENGDE;CASTILLO, ROSARIO SILVESTRE;YALAMOORI, VENKATACHALAPATHI;BALAJI, VITUKUDI NARAYANAIYENGAR;RAMNARAYAN, KALYANARAMAN |
| 分类号 |
A61K31/415;A61K31/42;A61K31/422;A61K31/423;A61K31/425;A61K31/427;A61P1/00;A61P9/00;A61P9/06;A61P9/10;A61P9/12;A61P11/08;A61P13/02;A61P15/00;A61P27/02;A61P27/06;A61P29/00;A61P35/00;A61P43/00;C07D261/14;C07D261/16;C07D261/20;C07D413/12;C07D413/14;C07D417/12;(IPC1-7):C07D261/14 |
主分类号 |
A61K31/415 |
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