| 发明名称 |
Minimum recognition unit of a PEM mucin tandem repeat specific monoclonal antibody |
| 摘要 |
The peptide EPPT (Glu-Pro-Pro-Thr)(SEQ I YD NO:1) selectively binds a mucin expressed by epithelial tumors. It may be incorporated into larger molecules, such as, peptides consisting of the sequence EPPT and further amino acids to form a peptide of up to 30 amino acids, and may be radiolabelled or used to guide toxins, etc. to cells expressing the mucin.
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| 申请公布号 |
US6174691(B1) |
申请公布日期 |
2001.01.16 |
| 申请号 |
US19980131053 |
申请日期 |
1998.08.07 |
| 申请人 |
CANCER THERAPEUTICS LIMITED |
发明人 |
COURTENAY-LUCK NIGEL STEPHEN |
| 分类号 |
A61K39/395;A61K38/00;A61P35/00;C07K1/00;C07K1/22;C07K5/113;C07K7/00;C07K7/06;C07K7/08;C07K14/00;C07K14/47;C07K16/00;C07K16/18;C07K16/30;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12P21/08;C12Q1/02;G01N33/53;G01N33/574;(IPC1-7):G01N33/574;A61K51/00;A61K36/14 |
主分类号 |
A61K39/395 |
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