发明名称 NEW ALPHA-HYDROXY FATTY ACID DERIVATIVE AND COMPOSITION FOR EXTERNAL USE
摘要 PROBLEM TO BE SOLVED: To obtain a composition for external use which is excellent in stability, has a low melting point, has not irritation to the skin and excellent in sense of use by including at least one specificα-hydroxy fatty acid derivative. SOLUTION: This composition is prepared by including about 0.01-60.0 wt.% of at least one kind selected fromα-hydroxy fatty acid derivatives (e.g. 2- palmitoyloxypalmitinic acid ethyl ester, etc.), of the formula (wherein R1 is a 10-24C alkyl; R2 is a 1-31C alkyl; and R3 is a 1-10C alkyl). The compound of the formula is obtained e.g. by reacting 2-hydroxypalmitic acid with ethanol while removing produced water and then by reacting palmitic acid chloride in the presence of pyridine. Theα-hydroxy fatty acid derivative can be used by being formulated in a skin composition such as lotion and emulsion, and a hairdressing composition such as shampoo and rinse.
申请公布号 JP2001010944(A) 申请公布日期 2001.01.16
申请号 JP19990187512 申请日期 1999.07.01
申请人 KANEBO LTD 发明人 KUSUMARU MASAFUMI;NAKATSUGAWA HIROKO;IWAMOTO YOSHIKO;IKEMOTO TAKESHI
分类号 A61K8/00;A61K8/30;A61K8/37;A61Q1/00;A61Q1/04;A61Q5/00;A61Q5/02;A61Q19/00;C07C69/675;(IPC1-7):A61K7/48;A61K7/00;A61K7/06 主分类号 A61K8/00
代理机构 代理人
主权项
地址