PHARMAZEUTISCH WIRKSAME VERBINDUNGEN UND LIPOSOME UND VERFAHREN ZU DEREN HERSTELLUNG

摘要

This invention provides a compound having the formula R<1>-Y<1>-CHZ<1>-CH(NY<2>Y<3>)-CH2-Z<2>, wherein: R<1> is a straight-chained alkyl, alkenyl or alkynyl group having from 8 to 19 carbon atoms in the aliphatic chain; Y<1> is -CH=CH-, -C PARALLEL C- or -CH(OH)CH(OH)-; Z<1> is OH or a conversion-inhibiting group; Z<2> is a conversion-inhibiting group; Y<2> is H, phenyl group, an alkylsubstituted phenyl group having from 1 to about 6 carbons in the alkyl chain, or an alkyl chain having from 1 to 6 carbons; Y<3> is H or a group having the formula -C(O)R<2> or -S(O)2R<2>; R<2> is a straight-chained alkyl, alkenyl, alkynyl group having from 1 to 23 carbon atoms in the chain; and when Z<2> is an amino, R<2> is an aliphatic chain having from 1 to 9 or from 19 to 23 carbon atoms in the aliphatic chain.