This invention is directed to bicyclic and tricyclic compounds which are selective antagonists for NPY (Y5) receptors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention provides a pharmaceutical composition made by combining a therapeutically effective amount of a compound of this invention and a pharmaceutically acceptable carrier. The invention provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention further provides the use of a compound of the invention for the preparation of a pharmaceutical composition for treati ng an abnormality, wherein the abnormality is alleviated by decreasing the activity of a human Y5 receptor.
申请公布号
CA2380866(A1)
申请公布日期
2001.01.11
申请号
CA20002380866
申请日期
2000.04.21
申请人
SYNAPTIC PHARMACEUTICAL CORPORATION;NOVARTIS AG
发明人
NOBLE, STEWART A.;SCHILLING, WALTER;YAMAGUCHI, YASUCHIKA;RUEGER, HEINRICH;BUHLMAYER, PETER;WONG, WAI C.;MARZABADI, MOHAMMAD R.