发明名称 |
DSP-3 DUAL-SPECIFICITY PHOSPHATASE |
摘要 |
Compositions and methods are provided for the treatment of conditions associated with cell proliferation, cell differentiation and cell survival. In particular, the dual-specificity phosphatase DSP-3, and polypeptide variants thereof that stimulate dephosphorylation of DSP-3 substrates, are provided. The polypeptides may be used, for example, to identify antibodies and other agents that inhibit DSP-3 activity. The polypeptides and agents may be used to modulate cell proliferation, differentiation and survival. |
申请公布号 |
WO0102581(A1) |
申请公布日期 |
2001.01.11 |
申请号 |
WO2000US10868 |
申请日期 |
2000.04.20 |
申请人 |
CEPTYR, INC.;LUCHE, RALF, M.;WEI, BO |
发明人 |
LUCHE, RALF, M.;WEI, BO |
分类号 |
G01N33/50;A61K39/395;A61K45/00;A61P3/00;A61P21/04;A61P35/00;A61P37/02;A61P43/00;C07K16/40;C12N1/15;C12N1/19;C12N1/21;C12N5/06;C12N5/10;C12N9/16;C12N15/09;C12N15/10;C12N15/11;C12N15/52;C12P21/08;C12Q1/02;C12Q1/42;C12Q1/68;G01N33/15;G01N33/53;G01N33/566;G01N33/577;G01N33/58;G01N33/68 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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