发明名称 |
GENE ENCODING CYCLIC LIPOPEPTIDE ACYLASE AND EXPRESSION OF THE SAME |
摘要 |
Determination of the base sequence in the coding domain of a cyclic lipopeti de acylase; determination of the full amino acid sequence of this acylase; an expression vector containing a gene encoding the above enzyme; and a process for producing the cyclic lipopeptide acylase by expressing the above expression vector in a host cell. Use of a transformant, which has an activi ty comparable to acylase obtained by culturing a conventional cyclic lipopeptid e acylase-producing strain and has been constructed genetic engineeringly, mak es it possible to shorten the culture time (i.e., the time for producing acylas e). |
申请公布号 |
CA2377793(A1) |
申请公布日期 |
2001.01.11 |
申请号 |
CA20002377793 |
申请日期 |
2000.06.28 |
申请人 |
FUJISAWA PHARMACEUTICALS CO., LTD. |
发明人 |
SHIBATA, TAKASHI;NOGUCHI, YUJI;YAMASHITA, MICHIO |
分类号 |
C12N1/21;C12N9/14;C12N15/55;C12P21/02 |
主分类号 |
C12N1/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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