| 发明名称 |
Method to select attenuated paramyxoviridae useful for vaccines and therapeutics |
| 摘要 |
<p>The present invention relates to a method using the cellular interferon-mediated antiviral response to select attenuated Paramyxoviridae. The invention also relates to a method to select viral nucleic acid sequence encoding for a mutated non-structural protein that is useful to produce an attenuated virus. The use of attenuated virus to develop vaccine is also described.</p> |
| 申请公布号 |
EP1067179(A1) |
申请公布日期 |
2001.01.10 |
| 申请号 |
EP19990401745 |
申请日期 |
1999.07.09 |
| 申请人 |
PIERRE FABRE MEDICAMENT |
发明人 |
CURRAN, JOSEPH;KOLAKOFSKY, DAN;GARCIN, DOMINIQUE;POWER, ULTAN |
| 分类号 |
A61P31/14;C07K14/155;C12N7/04;C12N15/40;C12N15/45;C12Q1/68;(IPC1-7):C12N7/04;C07K14/08;A61K39/155;C12Q1/70 |
主分类号 |
A61P31/14 |
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