发明名称 Use of aminoadamantane compounds as immunoregulators
摘要 wherein R1, R2, R3 and R4 are selected independently from each other from -NR5R6, -NR5R6R7+, hydrogen, aryl or heteroaryl with up to 7 ring members, C1-C20-alkyl, C1-C20-alkenyl and C1-C20-alkinyl, wherein the alkyl, alkenyl and alkinyl residues can be branched, unbranched or cyclized and optionally substituted with halogen, aryl or heteroaryl with up to 7 ring members, with the proviso that at least one of the residues R1, R2, R3 and R4 are represented by -NR5R6 or -NR5R6R7; andR5, R6 and R7 are selected independently from each other from hydrogen, aryl or heteroaryl with up to 7 ring members, C1-C20-alkyl, C1-C20-alkenyl, C1-C20-alkinyl, wherein the alkyl, alkenyl and alkinyl residues can be branched, unbranched or cyclized and optionally substituted with halogen, aryl or heteroaryl with up to 7 ring members, or R5 and R6, together with the nitrogen atom, form a heterocyclic group with up to 7 ring members;for the regulation of the activity of already activated neutrophils.
申请公布号 US6172116(B1) 申请公布日期 2001.01.09
申请号 US19980029335 申请日期 1998.07.31
申请人 MERZ + CO. GMBH & CO. 发明人 ELSTNER ERICH F.
分类号 G01N33/49;A61K31/00;A61K31/13;A61K31/132;A61K31/135;A61K31/14;A61K31/42;A61K38/06;A61P7/00;A61P29/00;A61P31/00;A61P31/18;A61P33/00;A61P33/02;A61P35/00;A61P37/00;A61P37/04;C07C211/03;(IPC1-7):A61K31/13 主分类号 G01N33/49
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