发明名称 Composition and methods employing it for the treatment of 5-HT-mediated disorders
摘要 The invention relates to a composition comprising a first component (a) which is (R)-3-N,N-dicyclobutylamino-8-fluoro-3,4-dihydro-2H-1-benzopyran-5-carboxamide hydrogen (2R,3R)-tartrate monohydrate and a second component (b) which is a 5-HT reuptake inhibitor, excluding citalopram and paroxetine. The invention is further directed to the preparation of the composition, pharmaceutical formulations containing said composition, and a method of treatment of affective disorders such as mood disorders and anxiety disorders with said composition, as well as a kit containing said composition.
申请公布号 US6172105(B1) 申请公布日期 2001.01.09
申请号 US19990351070 申请日期 1999.07.09
申请人 ASTRA AKTIEBOLAG 发明人 EVENDEN JOHN;THORBERG SETH-OLOV
分类号 C07D311/58;A61K31/35;A61K31/352;A61K31/4406;A61K31/445;A61K31/55;A61K45/00;A61P25/24;A61P25/26;(IPC1-7):A61K31/35;A61K31/40 主分类号 C07D311/58
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