| 摘要 |
PROBLEM TO BE SOLVED: To obtain the subject improver having effect of reducing total cholesterol levels and neutral lipid levels in the plasma and effect of increase in the excretion of both cholesterol and bile acid into feces by including a decomposition product of royal jelly formed by the action of protease. SOLUTION: This lipid metabolism improver comprises a decomposition product of royal jelly formed by the action of protease. The decomposition product consists mainly of a peptide pref. <=3,000 in molecular weight, being obtained by the following process: at least two kinds of protease preferably differing in site of action on a substrate are added either simultaneously or sequentially to a royal jelly suspension followed by holding the suspension at room temperature or higher to carry out an enzyme reaction; wherein the above two or more kinds of protease to be used are e.g. acidic protease, neutral protease, alkaline protease, each originated from microorganisms or plants, digestive enzymes derived from mammals such as pepsin and pancreatin. It is preferable that, when to be added to a drink or the like, the above decomposition product is at 0.5-3 wt.% on a dry basis. |
