| 发明名称 |
Methods of controlling beta dimer formation in hemoglobin |
| 摘要 |
The present invention relates to methods of controlling beta dimer formation in hemoglobin solutions by altering the metal binding site adjacent to the N-terminus of beta globins. The invention further relates to methods of producing stable, intramolecularly crosslinked beta globins by exposure to Ni(II) and oxone.
|
| 申请公布号 |
US6171826(B1) |
申请公布日期 |
2001.01.09 |
| 申请号 |
US19990230603 |
申请日期 |
1999.05.14 |
| 申请人 |
BAXTER BIOTECH TECHNOLOGY SARL |
发明人 |
LEVINE JOSEPH D.;APOSTOL IZYDOR A. |
| 分类号 |
C12N15/09;C07K14/805;C12N1/21;(IPC1-7):C12P21/06 |
主分类号 |
C12N15/09 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
