SCREENING METHOD OF ANTI-INFLAMMATORY CONTROL AGENT OR ANTI-CANCER CONTROL AGENT

摘要

PURPOSE: A screening method of anti-inflammatory control agent or anti-cancer control agent is provided, which develops new remedial agents against degenerative brain disease, senile disease, chronic disease, cancer and the like. CONSTITUTION: A screening method of anti-inflammatory control agent or anti-cancer control agent is characterized by screening controlling material of inflammation induction factor selected from the group of interleukin-1, interleukin-1 beta converting enzyme, interleukin-18 by detecting proliferation of T-helper cell which is induced specifically by interleukin-1. The T-helper cell is characterized by D10S cell. The controlling material of inflammation induction factor is characterized by activity repressor which represses interleukin-1 or blocks signal transfer by interleukin-1. The controlling material of inflammation induction factor is characterized by activity promoter or activity repressor of interleukin-1 beta converting enzyme.