METHOD AND GENETIC THERAPEUTIC AGENT FOR CURING BENIGN PROSTATIC HYPERPLASIA

摘要

PURPOSE: A method and genetic therapeutic agent for curing BPH(Benign Prostatic Hyperplasia) is provided to dramatically inhibit the growth of the prostatic gland texture by giving medication to the prostatic gland texture with an adenovirus vector(Ad/OC/HSV-TK) including an HSV-TK(herpes simplex virus- thymidine kinase) gene and an osteocalcin promoter. CONSTITUTION: A method for curing a benign prostatic hyperplasia is a TUMAP(TransUrethral Molecular Ablation of Prostate) giving a genetic therapeutic agent to the prostatic gland texture using an ultrasound, wherein the genetic therapeutic agent includes an adenovirus vector(Ad/OC/HSV-TK) and a genetic therapeutic agent causing an apoptosis. The method for curing the benign prostatic hyperplasia is a TRMAP(TransRectal Molecular Ablation of Prostate) giving the genetic therapeutic agent to the prosatic gland texture using the ultrasound.