METHODS OF TREATING FUNGAL INFECTIONS WITH INHIBITORS OF NAD SYNTHETASE ENZYME

摘要

The present invention provides methods of treating or preventing fungal infections in a host comprising administering a treatment effective or treatment effective amount of a yeast NAD synthetase inhibitor compound. The invention further provides a method of killing yeast comprising administring a yeast NAD synthetase compound that selectively binds to catalytic sites in yeast whereby the yeast is killed.