COMPOUNDS AS SELECTIVE AGONISTS AT ALPHA 2B OR 2B/2C ADRENERGIC RECEPTORS

摘要

Compounds having adrenergic activity which are a selective agonists for one or both of the α2B and α2C adrenoceptor receptor subtypes in prefrence to the α2A adrenoceptor receptor subtype; the active compound being selected from the group consisting of compounds having formula (I) wherein the dotted lines represent optional bonds; R is H or lower alkyl; X is S or C(H)R1, wherein R1 is H or lower alkyl, Y is O, N, S, (CR12)y, wherein y is an integer of from 1 to 3, -CH=CH- or -Y1CH2-, wherein Y1 is O, N or S.