| 摘要 |
<p>Benzimidazole compounds represented by general formula (I) or salts thereof, which exhibit an inhibitory activity against the conversion of macrophages into foam cells and are useful as the active ingredient of drugs to be used in the prevention and/or treatment of arteriosclerosis wherein R1 is a substituent on the benzene ring which is selected from the group consisting of hydrogen, halogeno, lower alky, and lower alkoxy; R2 is hydrogen, alkyl, or acyl; and R3 is a substituent on the ring containing nitrogen and Z; Z is a divalent group constituting a five- or six-membered ring; L is C¿4?-C8 alkylene or an ethylene-oxy group represented by the general formula: (CH2CH2O)nCH2CH2 (wherein n is 1 or 2); and X is O or S.</p> |
